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Molecular Mechanisms of Synthetic Lethality: A Clinical Review of PARP Inhibition in BRCA-Mutated Malignancies
Medically Reviewed by: Dr. Salma Elreedy, Clinical Oncologist, Sphinx Cure Oncology Center. Fact-Checked by: Generic Oncology Editorial Team. Synthetic lethality is a genetic phenomenon where the simultaneous loss of function in two separate genes results in cell death, while the…